Johannes
Krause of the University of Tübingen (Germany) deciphered the genome
sticks Hansen (Mycobacterium leprae), the causative agent of medieval
leprosy.
Chronicles indicate that leprosy was widespread in Europe in the first half of the Middle Ages. By the late 16th century, it came to an epidemic, and the reasons for this remain unknown.
Krause and his colleagues studied the remains of the inhabitants of Sweden, Denmark and England, who died of leprosy in the 11-14 centuries AD. Scientists separated the small pieces from the teeth, and tried to remove the fragments of bacterial DNA. To their surprise, the Europeans enamel contained a surprising amount of genomic fragments bacilli, ten times more than expected.
This allowed them to recover the complete genome of a microbe with an accuracy higher than the standard for live bacteria to 5 times. The scientists compared the structure of its DNA with the genomes of 11 modern species of Mycobacterium leprae. It was found that the genomes of microbes were virtually identical. This suggests that this microbe was originally highly contagious to humans, but over time it has lost force as human immune system has adapted to it faster than a bacterium
med-news-pro.blogspot.ru/
med-news-pro
med-news
Chronicles indicate that leprosy was widespread in Europe in the first half of the Middle Ages. By the late 16th century, it came to an epidemic, and the reasons for this remain unknown.
Krause and his colleagues studied the remains of the inhabitants of Sweden, Denmark and England, who died of leprosy in the 11-14 centuries AD. Scientists separated the small pieces from the teeth, and tried to remove the fragments of bacterial DNA. To their surprise, the Europeans enamel contained a surprising amount of genomic fragments bacilli, ten times more than expected.
This allowed them to recover the complete genome of a microbe with an accuracy higher than the standard for live bacteria to 5 times. The scientists compared the structure of its DNA with the genomes of 11 modern species of Mycobacterium leprae. It was found that the genomes of microbes were virtually identical. This suggests that this microbe was originally highly contagious to humans, but over time it has lost force as human immune system has adapted to it faster than a bacterium
med-news-pro.blogspot.ru/
med-news-pro
med-news
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