Renal denervation reduces blood pressure and reduces the stiffness of blood vessels in hypertensive patients resistant to drug therapy. These are the conclusions of Dr. Claes Franzen (Klaas Franzen) of the University Hospital Schleswig-Holstein (University Hospital of Schleswig-Holstein) in Germany. They were presented at the Congress of the European Society of Cardiology (European Society of Cardiology) 2012.
Decades of malignant hypertension was treated by surgical operation - thoracolumbar splanhektomii (excision splanchnic nerves). It is kind of sympathectomy, proposed for the treatment of hypertension in 1938. "More than half of the patients after splanhektomii a marked decrease in blood pressure, - says Franzén. - However, this method of treatment there were serious side effects - orthostatic hypotension, anhidrosis (lack of sweating) and violation of the intestine. After creating a number of effective antihypertensive drugs splanhektomiya gone down in history, and for a long time, no one thought of this method. "
In 2009, the concept of sympathectomy was slightly reorganized, resulting in the technique such as percutaneous intravazalnaya renal sympathetic denervation with a catheter (renal denervation). The method is well established for the treatment of patients with malignant hypertension, are not susceptible to the drugs. Recent studies have shown that within 6 months after renal denervation reduces systolic blood pressure by an average of 32, and diastolic - 12 mm Hg. Art. Since the method is non-invasive, it compares favorably with previous techniques splanhektomii, it had a much smaller number of side effects and a shorter recovery time patient.
In a study conducted by Dr. Frantsenom participated 21 patients with hypertension, the drug resistance (13 men and 8 women, mean age - 64 years). All participants at baseline systolic blood pressure greater than 150 mm Hg. Art. Each patient underwent renal denervation. In general, the systolic blood pressure of all participants decreased by 7,6-9,5 mm Hg. Art. 3 months after surgery and another 5,4-6,6 mm Hg. Art. after six months.
Furthermore, renal denervation improved hemodynamics and condition of the walls of blood vessels. During prolonged hypertension develops stiffness of the vascular wall, and the arteries lose their elasticity. Because of this increased pulse wave velocity. The results showed that all patients who underwent renal denervation, pulse wave velocity decreased by an average of 1 m / s at 3 months or more at 1 m / s - six months after the operation.
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Decades of malignant hypertension was treated by surgical operation - thoracolumbar splanhektomii (excision splanchnic nerves). It is kind of sympathectomy, proposed for the treatment of hypertension in 1938. "More than half of the patients after splanhektomii a marked decrease in blood pressure, - says Franzén. - However, this method of treatment there were serious side effects - orthostatic hypotension, anhidrosis (lack of sweating) and violation of the intestine. After creating a number of effective antihypertensive drugs splanhektomiya gone down in history, and for a long time, no one thought of this method. "
In 2009, the concept of sympathectomy was slightly reorganized, resulting in the technique such as percutaneous intravazalnaya renal sympathetic denervation with a catheter (renal denervation). The method is well established for the treatment of patients with malignant hypertension, are not susceptible to the drugs. Recent studies have shown that within 6 months after renal denervation reduces systolic blood pressure by an average of 32, and diastolic - 12 mm Hg. Art. Since the method is non-invasive, it compares favorably with previous techniques splanhektomii, it had a much smaller number of side effects and a shorter recovery time patient.
In a study conducted by Dr. Frantsenom participated 21 patients with hypertension, the drug resistance (13 men and 8 women, mean age - 64 years). All participants at baseline systolic blood pressure greater than 150 mm Hg. Art. Each patient underwent renal denervation. In general, the systolic blood pressure of all participants decreased by 7,6-9,5 mm Hg. Art. 3 months after surgery and another 5,4-6,6 mm Hg. Art. after six months.
Furthermore, renal denervation improved hemodynamics and condition of the walls of blood vessels. During prolonged hypertension develops stiffness of the vascular wall, and the arteries lose their elasticity. Because of this increased pulse wave velocity. The results showed that all patients who underwent renal denervation, pulse wave velocity decreased by an average of 1 m / s at 3 months or more at 1 m / s - six months after the operation.
Med-NEws Medicine
Med-NEws Medicine blogspot
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